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Quick summary

Type of medicine

Anti-malarial

Generic

No

Active Ingredient

Mefloquine

Effective within

Start taking 10 days before travel

Works by

Targeting and inhibiting malaria parasites

Side effects

Sleeping problems, dizziness, headache, nausea, vomiting, diarrhea, stomach ache

Medication details

Description

Lariam, also known as mefloquine, is a medication used to prevent and treat malaria. Malaria is a serious and potentially life-threatening disease that is spread by the bite of infected mosquitoes.

Lariam works by killing the malaria parasites in your blood and is most effective when taken before, during, and after exposure to the disease. It is important to start taking Lariam before you travel to an area where malaria is common and to continue taking it for the duration of your trip and for 4 weeks after you return.

This medication is well-tolerated by most people and has a low risk of side effects. However, some people may experience mild side effects such as nausea, dizziness, and headaches. If you experience any severe or persistent side effects, you should seek medical attention immediately.

Lariam is a safe and effective way to prevent and treat malaria. If you are traveling to an area where malaria is common, talk to your doctor about whether Lariam is right for you. #MalariaPrevention #Lariam

Directions

Before starting your Lariam regimen, it's important to follow specific directions to ensure its optimal effectiveness. Lariam tablets should be taken with plenty of water, preferably after a meal. Dosage instructions differ based on whether Lariam is used for malaria prevention or treatment. For prevention, initiate the tablets 10 days before your departure and continue weekly doses throughout your stay, plus 4 weeks after returning. Malaria treatment dosages vary by weight and duration of exposure. Children's doses are adjusted according to their weight.

Ingredients

The active ingredient in Lariam is mefloquine, which belongs to the class of antimalarial drugs. Mefloquine's mechanism of action involves targeting malaria parasites, preventing their growth and spread within the body. Its effectiveness is essential in combatting the diverse strains of malaria found in various regions. While mefloquine is the primary component, Lariam tablets also contain other ingredients like poloxamer, microcrystalline cellulose, lactose monohydrate, maize starch, crospovidone, ammonium calcium alginate, talc, and magnesium stearate.

Side Effects

While Lariam's efficacy against malaria is crucial, it's essential to be aware of potential side effects that may arise. Common side effects include sleeping problems, dizziness, headache, vision issues, nausea, vomiting, diarrhea, and stomach ache. However, some individuals may experience more serious side effects, including mental health concerns like depression, anxiety, hallucinations, and self-endangering behavior. If any symptoms are concerning, promptly consult your healthcare provider.

Warnings

Lariam may lead to severe mental problems in certain individuals. Serious symptoms, such as suicidal thoughts, paranoia, and abnormal behavior, should be immediately reported to your healthcare provider. Inform your doctor about any pre-existing conditions, such as epilepsy, heart problems, liver or kidney issues, or previous allergic reactions. In some cases, side effects like dizziness and balance problems may persist even after discontinuing Lariam. This emphasizes the importance of consistent communication with your healthcare provider.
Special Considerations for Pregnant Women and Breastfeeding:
Pregnant women should avoid Lariam due to potential risks to both the mother and the unborn child. Malaria prevention strategies should be explored that do not involve Lariam. Breastfeeding women should also avoid Lariam, and alternative measures should be discussed with a healthcare provider.
Driving and Using Machinery while Taking Lariam:
Lariam can potentially affect your ability to perform tasks requiring alertness, coordination, and spatial awareness, such as driving or operating machinery. If you experience dizziness, vertigo, or other balance-related issues, exercise caution and consult your healthcare provider before engaging in such activities.
Storing Lariam Properly:
Maintaining the integrity of Lariam tablets is crucial for their efficacy. Store Lariam below 30ºC, in a dry place, and away from the reach of children. Proper storage ensures that the medication remains effective throughout its shelf life.
Reporting Side Effects:
If you experience any side effects while taking Lariam, promptly communicate with your healthcare provider. Timely reporting not only helps address your concerns but also contributes to the overall understanding of the medication's safety profile.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Aug 24, 2023, 3:30 pm

How it works

Start a consultation for your condition, select a treatment option, and our in-house clinicians will review and prescribe if suitable. Expect your order within 1-3 working days.

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FAQs

Please read our FAQs page to find out more.

Who should take Lariam for malaria prevention?

Lariam is recommended for individuals traveling to tropical regions where there is a risk of contracting malaria. It is particularly valuable in areas with challenging-to-treat strains of malaria. Consult your healthcare provider to determine its suitability for your travel plans.

Can pregnant or breastfeeding women take Lariam?

Pregnant and breastfeeding women are advised to avoid Lariam due to potential risks to both the mother and the unborn child or infant. Alternative malaria prevention or treatment options should be explored in consultation with a healthcare provider.

Can I drive or operate machinery while taking Lariam?

Lariam can potentially affect your ability to perform tasks requiring alertness and coordination. If you experience dizziness, vertigo, or other balance-related issues, exercise caution and consult your healthcare provider before engaging in such activities.

How do I report side effects of Lariam?

If you experience any side effects while taking Lariam, promptly communicate with your healthcare provider. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard.

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